Hello Bernard:
I have spoken to Fuji a bit on this, US support. The "instant AF" should allow you to still use AF in the M mode, but with my X-Pro2, this method is not accurate and provides slightly softer images, especially with the 16-55, and 50-140 on the wider end. As you get closer to the far side, 35mm and up on the 16-55 and 80-90mm and up on the 50-140, the "instant AF" button seems to work as it is supposed to. On the X-T1, I do not see the same issues, as both test images I have shot will be the same. For sure, if you obtain a focus solution in S mode with AF, and then switch to M Mode, your lens will drop out of focus.
The difference between S mode and normal AF (half press of the shutter button) and M mode and "instant AF" is close, most of the time, but it's not identical. so I am going to send some images off to Fuji soon.
I also realized while doing this, that due to the design of the Fuji Cameras, and their fly by wire AF motors, none of the Fuji lenses are really good for night work, at least stacking for star trails, they might fair better on milky way work.
The X-Pro2's limited battery life, would only allow about 45 minute of continuous shooting, maybe 1 hour, after which you would need to change the battery out. This requires you to turn the camera off, thus the focus motor will reset and when the camera is turned back on, you are out of focus and trying to manually focus at night is next to impossible. Even if the camera is turned of in M mode, the lens will loose it's focus when you turn on the camera. This is unlike any other system I have used, Nikon, Canon or Sony.
The X-T1 with the grip will work much longer, most likely up to 2.5 hours, with 2 batteries installed, but it has the same issues with the lenses.
At least the 14mm F 2.8 does have a AF clutch on the lens, (which more of the Fuji lenses has this), so you can totally control the manual focus process without the camera getting involved. And you can turn off the camera (with the lens clutched to non AF) and then back on and the lens will not pop out of focus. Which is something all other Fuji lenses do, ( at least the ones I have tried).
Paul C