Matt, I simply use Lightroom standard sharpening for matte, 100% jpeg quality. If I do not have enough pixels, I enter 150 ppi, as they say between 100-150 ppi is sufficient for canvas. Never had issues with sharpness with them (nor anything else for that matter). I usually print 20x30, and I did it from 8 Mpx (Canon 20D), 10 Mpx (40D), 18Mpx (60D), 20 Mpx (6D) and can hardly see the difference. I printed 24x36 from 8 Mpx and 30x40 from 15 Mpx (Canon G10) and still do not see much difference. As an aside, none of my art show visitors ever raised any issue about sharpness. On the contrary, they admired the amount of details that matter.