I'm still back in the dark ages with Photoshop 6 so can't help you with features that may be in later versions. Also have no experience with b&w film scans. Nevertheless some of what I've used may still be of use.
Photoshop has several options under Filters/Noise. The least intrusive is Despeckle. Try applying one or two passes to individual channels (red, blue, or green - whichever shows the most pronounced graininess). The Median Cut filter might be worth experimenting with, as well. For heavier artillery, as Rich mentions you can try Neat Image or Noise Ninja on your scan files.
Another approach is simply to avoid sharpening the grain. Bruce Fraser's
edge sharpening method may seem a bit daunting: just record it once as a macro then re-use at will.
Mike:
You should also scan at no higher a resolution than necessary
A 4x5 shooter acquaintance and I had this out a few years back. This is what we ended up with:
The detail in a film frame is literally composed out of grain (or dye clouds). The more you magnify the frame - meaning the greater the scan resolution - the more you magnify both its grain
and its detail. Conversely, as you suggest using a lower resolution returns less grain ... but also less detail. One of the things that detail does for you is define your edges, IOW creates acutance. So in theory at least, the lower your scan res the more sharpening you'll need to apply to restore acutance, and the more sharpening you apply the more you're further destroying your image.
Whether this is a problem or not depends on the individual image and on your personal tastes. An alternative approach would be to scan at max res, then use intelligent noise/grain reduction, such as Neat Image or Noise Ninja, to eliminate as much graininess as possible in the regions inside the edge boundaries.
If anyone is really serious about scanning, I recommend trying both approaches on a number of images to see which you are happier with. I have had far better luck with the high res scan approach, but others, like you, the opposite. Perhaps it just comes down to how much acutance a person needs in order to feel an image is adequately crisp.
Yours in analog counterrevolutionary spirit
Nice! Unfortunately, I finally succumbed to the digital side of the force last summer, but I wish you well.