I've noticed a repeatable behavior while processing some recent images.
It seems, that the odd moving of sliders but without image (or numeric) reaction, happens only (or mainly?) in the following instance: I don't initially click on the slider and move it, but click somewhat (no great distance) next the slider and expect the slider to snap to that position. It that case, the slider moves, but the Develop module doesn't seem to acknowledge the new position by adjusting the math. (Poorly described, I know, but I'm no computer wiz.)
Only when I grab the slider from the onset and move it, will even tiny adjustments be numerically registered and shown on the screen! I'd adopted the method of clicking off to one side of a slider and then actually sliding it, some LR iterations ago.
I never noticed the current behavior of LR6. So, bottom line for me - I'll need to adjust my works style, which shouldn't be difficult. And I'll keep GPU acceleration clicked off. It would seem, my problem was based on a rather unorthodox method of (quickly?) moving sliders.